The Khan et al. 7:1444-1448, (2011) article is featured on the cover page of the July issue of the journal "Ophthalmology".

About me

After obtaining an M.Sc. in Biochemistry from the University of Peshawar, I worked as a Scientific Officer at the National Institute of Health, Islamabad, Pakistan. I then proceeded to USA to work towards my Ph.D in the Department of Biochemistry & Molecular Biology, University of North Texas, Denton, Texas, USA.

During my stay in the US I worked as a Research Assistant at the Department of Biochemistry, University of North Texas and as a Research Associate at the Department of Microbiology & Immunology, Texas College of Osteopathic Medicine, Fort Worth, Texas, USA. After completing my Ph.D. I came back to Pakistan and joined Dr. A. Q. Khan Research Laboratories as a Senior Scientific Officer and was subsequently promoted to the position of Principal Scientific Officer. From 1998 to 2001 I worked for a while, with Dr. Chris Tyler-Smith at the Department of Biochemistry, University of Oxford, Oxford, UK in the lab of Prof. E.M. Southern. In 2002 I joined Shifa College of Medicine as Assistant Professor of Biochemistry and in 2003 was promoted to the post of Associate Professor & also appointed as the Director of PCR Labs. .....Read more

About me

Brief History

After obtaining an M.Sc. in Biochemistry from the University of Peshawar, I worked as a Scientific Officer at the National Institute of Health, Islamabad, Pakistan. I then proceeded to USA to work towards my Ph.D in the Department of Biochemistry Molecular Biology, University of North Texas, Denton, Texas, USA.

During my stay in the US I worked as a Research Assistant at the Department of Biochemistry, University of North Texas and as a Research Associate at the Department of Microbiology & Immunology, Texas College of Osteopathic Medicine, Fort Worth, Texas, USA. After completing my Ph.D. I came back to Pakistan and joined Dr. A. Q. Khan Research Laboratories as a Senior Scientific Officer and was subsequently promoted to the position of Principal Scientific Officer. From 1998 to 2001 I worked for a while, with Dr. Chris Tyler-Smith at the Department of Biochemistry, University of Oxford, Oxford, UK in the lab of Prof. E.M. Southern. In 2002 I joined Shifa College of Medicine as Assistant Professor of Biochemistry and in 2003 was promoted to the post of Associate Professor & also appointed as the Director of PCR Labs. In 2004 I was appointed as the Research Director of Shifa College of Medicine. In 2005 I joined COMSATS University as Professor of Biosciences and also served as the Chair of the Department of Biosciences till 2008 when I was appointed as the Dean of the Faculty of Sciences. In the meanwhile I am continuing to serve as the Research & PCR Lab Director at the Shifa College of Medicine.

My training has been in Chemical pathology, Biochemistry, Biomedical & Genetic Engineering. I have completed courses in DNA Cloning & Sequencing from the University of Portsmouth, Portsmouth, United Kingdom. In Polymerase Chain Reaction (PCR) Applications from the American Type Culture Collection (ATCC), Rockville, Maryland, USA., a course in operation of the DNA sequencer Model 377 from Applied Biosystems, A Division of Perkin Elmer American, at the Foster City, USA and a fourth course in DNA Sequencer Training from the Beckman centre, High wycombe, UK.

My research specialization includes Enzymology, Population & Molecular Genetics and Molecular Pathology. I am particularly interested in searching for the molecular basis of all forms of inherited diseases in the Pakistani populations and my research group, comprising of 4 PhD, 5 MS students, 4 Assistant Professors and 3 Foreign Professors, is currently working on a number of different projects along these lines.

 

Professional Experience

 

2012-present               NUST                               Islamabad, Pakistan

Visiting Distinguished NUST Professor

·    Atta-ur-Rahman School of Applied Biosciences, National University of Science & Technology

2011-present    CIIT     Islamabad, Pakistan
Dean
·    Research & Innovation, COMSATS Institute of Information Technology

2005-present    CIIT     Islamabad, Pakistan
Professor of Biosciences

·    Department of Biosciences, COMSATS Institute of Information Technology.

2008-2011        CIIT     Islamabad, Pakistan
Dean

·    Faculty of Sciences, COMSATS Institute of Information Technology.

 

2010     CIIT     Islamabad, Pakistan
In-charge (Director), Islamabad Campus

·    COMSATS Institute of Information Technology.

 

2009-2010        CIIT     Islamabad, Pakistan
In-charge Student Affairs, Islamabad Campus

·    COMSATS Institute of Information Technology.

 

2009-2009        CIIT     Islamabad, Pakistan
In-charge (HR), Islamabad Campus

·    COMSATS Institute of Information Technology.

 

2007-2010        CIIT     Islamabad, Pakistan
In-charge Bio-Physics Block, Chak Shahzad Campus

·    Bio-Physics Block, COMSATS Institute of Information Technology.

 

2005-2008        CIIT     Islamabad, Pakistan
Chairman of Biosciences

·    Department of Biosciences, COMSATS Institute of Information Technology.

 

2003-present    SCM    Islamabad, Pakistan
Research Director & PCR Lab Director

·    Department of Research and PCR Lab, Shifa College of Medicine.

 

2002-2005        SCM    Islamabad, Pakistan
Research Director, PCR Lab Director & Associate Professor of Biochemistry

·    Departments of Research and of Biochemistry, Shifa College of Medicine.

 

1998-2001                    Islamabad, Pakistan
Principal Scientific Officer

·    Biomedical & Genetic Engineering Laboratories.

 

1998-2001        University of Oxford      Oxford, UK
Wellcome Trust Fellow

·    Department of Biochemistry, University of Oxford.

1993–1998                    Islamabad, Pakistan
Senior Scientific Officer

·    Biomedical & Genetic Engineering Laboratories.

1988–1993        TCOM Fort Worth, TX, USA
Research Associate

·    Department of Microbiology & Immunology, Texas College of Osteopathic Medicine.

1987-1988                  UNT                                     Denton, TX, USA
Research Assistant

·     Department of Biochemistry, University of North Texas

1986-1987                    NIH                              Islamabad, Pakistan
Scientific Officer (Chemical Pathology)

·    Department of Public Health, National Institute of Health

Courses and Workshops attended

  • "DNA Sequencer Training" Beckman centre, High wycombe, UK, 2006
  • "Model 377 Training Course", Applied Biosystems, A Division of Perkin Elmer American, Foster City, USA, 1996.
  • "Polymerase Chain Reaction (PCR) Applications", American Type Culture Collection (ATCC), Rockville, Maryland, USA, 1994.
  • "DNA Cloning & Sequencing Workshop 1993", University of Portsmouth, UK. Supervised by Dr. Keith Firman.

Grants and Awards

  • 2011-2013   “Genetic Analysis of Recessive Retinitis Pigmentosa in Pakistani Population”.  Rs. 1.99 Million under the Pakistan Academy of Sciences (PAS) Research Grant Award as PI, grant no. PAS/I-9/Project.
  • 2011-2013   “Assessment of Genetic Risk Factors of Glaucoma”.  Rs. 1.32 Million under the Pakistan Science Foundation (PSF) Grant Award as PI, grant no. PSF/RES/C-COMSATS/MED(280).
  • 2009-2010   “Genetic Studies of Inherited Disorders”.  Rs. 1.0 Million Core Grant from the Shifa College of Medicine as PI.
  • 2007-2010   “The Molecular Basis of High Blood Cholesterol in Select Families”.  Rs. 5.21 Million under the Higher Education Commission (HEC) National Research Program for Universities (NRPU) Grant Award as PI, grant no. 934.
  • 2006-2009   “Mapping the Genes Responsible for Autosomal Recessive Retinitis Pigmentosa”.  Rs. 5.964 Million under the Higher Education Commission (HEC) National Research Program for Universities (NRPU) Grant Award as PI, grant no. 530.
  • 2006-2006   “Strengthening of Molecular Genetics Laboratory of Biosciences CIIT Islamabad”.  Rs. 0.677 Million under the HEC Lab Up-gradation Grant Award as PI.
  • 2004-2006   “Association of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Gene Polymorphisms with Myocardial Infarction”.  Rs. 0.221 Million under the Shifa College of Medicine Research Grant Award as PI.
  • 2004-2005   “Genetic Basis of PCOS”.  Rs. 0.404 Million under the Shifa College of Medicine Research Grant Award as PI.
  • 2008   Tamgha-i-Imtiaz by the President of Islamic Republic of Pakistan.
  • 1998-2001   Wellcome Trust Fellowship, UK.
  • 1987-1988   Robert A. Welch Foundation, USA, Fellowship for PhD studies.

Membership

  • Fellow of the Pakistan Academy of Sciences, 2009-for life.
  • Vice-Chairman of the Ethics Committee of Shifa International Hospital (SIH) and Shifa College of Medicine (SCM) 2012-present.
  • Vice-Chairman of the Institutional Review Board of Shifa International Hospital (SIH) and Shifa College of Medicine (SCM) 2012-present.
  • Convener of the CIIT Research Grant Program 2011-present.
  • Convener of the Campus Selection Committee, COMSATS Institute of Information Technology (CIIT) 2009-2010.
  • Convener of the Board of Faculty of Science, COMSATS Institute of Information Technology (CIIT) 2008-2011.
  • Convener of the Board of Studies of the Department of Biosciences, COMSATS Institute of Information Technology (CIIT) 2005-2008.
  • Member of the Higher Education Commission (HEC) committee for Travel Grant to Teachers, Staff & Students registered for PhD & MPhil/MS leading to PhD 2011-present.
  • Member of the Higher Education Commission (HEC) Tenure Track System (TTS) Committee 2011-present.
  • Member of the Higher Education Commission (HEC) Visiting Scholar Program (VSP) Selection Committee 2010-2011.
  • Member of the Working Group constituted by Planning Commission GoP on “Technology Driven Development” 2009-2010.
  • Member of the System-Wide Committee (SWC), COMSATS Institute of Information Technology (CIIT) 2009-2010.
  • Member of the WHO/EMRO Health Genomics and Biotechnology grant review committee, Egypt 2009.
  • Member of the Finance and Planning Committee (F&PC), COMSATS Institute of Information Technology (CIIT) 2008-2011.
  • Member Board of Governors COMSATS Institute of Information Technology (CIIT) 2008-2010.
  • Member Core Group of Life Sciences of the Higher Education Commission (HEC) 2008-2009.
  • Member of the Pakistan Science Foundation (PSF) Technical Committee on Medical Sciences 2007-2010.
  • Member of the committee for the establishment of the National Institute of Nanoscience and Technology 2007.
  • Member of the CIIT Research Grant Program 2006-2010.
  • Member CIIT Board of Advance Studies (BASAR) 2006- present.
  • Member of the Higher Education Commission (HEC) Committee on Microbiology, Biotechnology and Genetic Engineering.
  • Member of the Ethics Committee of Shifa International Hospital (SIH) and Shifa College of Medicine (SCM) 2002-present.
  • Member of the Institutional Review Board of Shifa International Hospital (SIH) and Shifa College of Medicine (SCM) 2002-present.
  • Member of the Shifa Tameer-i-Millat University Program Development Team.
  • Member of the LUMS SSE Virtual Program Development Team.
  • Member of the Committee of Courses for the Centre for Advanced Forensic Sciences, Allama Iqbal Open University.
  • The Human Genome Project (HUGO), UK 1998-present.
  • Lecturer The Human Genome Project (HUGO), UK.
  • Member of the Editorial Board World Journal of Ophthalmology.

Graduate Students Supervised

  1. Muhammad Imran, thesis title "Molecular Genetic Elucidation of Inherited Retinal Diseases".
  2. Muhammad Ajmal, thesis title "Genetic Basis of Inherited Eye Diseases".
  3. Nosheen Fazal, thesis title "Association Studies of Antioxidant Pathway Genes with Retinopathy".
  4. Saba Saleem, thesis title "Angiotensin Converting Enzyme and Plasminogen Activator Inhibitor-1 Association Studies with Retinopathy".
  5. Syeda Hafiza Benish Ali, thesis title "Single Nucleotide Polymorphism-based Association Studies of Bladder Cancer Patients".
  6. Waqas Ahmed, thesis title "Genetic Studies of Cardiovascular Diseases".
  7. Sobia Ajaz, thesis title "Comparative Computer Analysis of Promoter Architecture of Expression Pattern of Plant Genes".
  8. Saadia Arshad, thesis title "Comparative Analysis and Identification of Co-expressed Genes in Related and Distant Species".
  9. Moeen Riaz, thesis title "Association of Myocardial Infarction with Single Nucleotide Polymorphisms in the Platelet and Hemostasis System Genes".
  10. Javaria Asghar, thesis title "Study of the Genetic Causes of Glaucoma in Pakistani Patients".
  11. Hina Iqbal, thesis title "Genetic Analysis of Autosomal Recessive Mental Retardation (ARMR) in Pakistani Kindred".
  12. Ahmed Sadeque, thesis title "Analysis of Mutation Causing Retinitis Pigmentosa in Select Families".
  13. Maleeha Azam, thesis title "The Genetic Analysis of Retinal Dystrophies in Selected Pakistani Families".
  14. SajeelaYousuf, thesis title "Analysis of DNA Repair and Tissue Remodeling Genes in Glaucoma Patients".
  15. Hussain Mustatab Wahedi, thesis title "Mapping of Genes Involved in Alopecia with Mental Retardation Syndrome (APMR) and Autosomal Recessive Non-Syndromic Mental Retardation (ARNSMR) in Pakistani Families".
  16. Sobia Shafique, thesis title "Study of the Genetic basis of Glaucoma in the Pakistani Population".
  17. Humaira Ayub, thesis title "Study of APOC3, eNOS& Normal Population of Pakistan".
  18. Waqas Ahmed, thesis title "Association of the tissue – Plasminogen Activator (t-PA) and Plasminogen Activator Inhibitor-1 (PAI-1) Gene Polymorphism with Myocardial Infarction".
  19. Yasmeen Badshah, thesis title "Prevalence of Virulence Factors among Extra intestinal Clinical Isolates of Escherichia coli Obtained from Clinically Diagnosed Urinary Tract Infection Patients & Molecular Pathogenesis".
  20. Ayesha Malik, thesis title "Exclusion Analysis of Retinitis Pigmentosa Genes".
  21. Muhammad Imran Khan, thesis title "Candidate Gene Analysis of Retinitis Pigmentosa".
  22. Shazia Michael, thesis title "Pathogenesis of Vascular Risk Factors in Glaucoma".
  23. Rabab Satti, thesis title "Screening of Hepatitis C Virus in General Pakistani Population".
  24. Sanam Bashir, thesis title "Genotyping of Hepatitis C Virus among HCV Patients in Pakistani Population".
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